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Stony coral tissue loss disease (SCTLD) is a disease of corals that first appeared off the southeast coast of Florida in 2014. It originally was described as white plague disease. By 2019 it had spread along the Florida Keys and had appeared elsewhere in the Caribbean Sea. The disease destroys the soft tissue of at least 22 species of reef-building corals, killing them within weeks or months of becoming infected. The causal agent is unknown but is suspected to be either a bacterium or a virus with a bacterium playing a secondary role. The degree of susceptibility of a coral, the symptoms, and the rate of progression of the disease vary between species. Due to its rapid spread, high mortality rate, and lack of subsidence, it has been regarded as the deadliest coral disease ever recorded, with wide-ranging implications for the biodiversity of Caribbean coral reefs.

Tianzhou 4 was the fourth mission of the Tianzhou-class uncrewed cargo spacecraft, and the third resupply mission to Tiangong Space Station carrying 5 tons of cargos and 1 ton of propellant. It is the largest load capacity cargo spacecraft that is on active duty. It launched on 9 May 2022, docking successfully with the Tiangong space station at the aft port 6 hours after launch. Like previous Tianzhou missions, the spacecraft launched from the Wenchang Satellite Launch Center in Hainan, China on a Long March 7 rocket.